Burn Translational Research
- Shedding of the endothelial glycocalyx is quantitatively proportional to burn injury severity
- Luker JN, Vigiola Cruz M, Carney BC, Day A, Moffatt LT, Johnson LS, Shupp JW.
- Ann Burns Fire Disasters. 2018 Mar 31;31(1):17-22.
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Rationale for inclusion: Translation of trauma work looking at shock related endothelial damage to the burn population. Dose response of endothelial damage may suggest a mechanism behind burn-related vasodilatory shock
CAVEAT: Animal work
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- Plasma neutrophil gelatinase-associated lipocalin as early biomarker for acute kidney injury in burn patients
- Hong DY, Lee JH, Park SO, Beak KJ, Lee KR
- Hong DY, Lee JH, Park SO, Baek KJ, Lee KR. Plasma neu- trophil gelatinase-associated lipocalin as early biomarker for acute kidney injury in burn patients. J Burn Care Res 2013;34:e326–32.
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Rationale for Inclusion: Renal failure remains a large contributor to burn mortality. This prospective study provides a plasma based marker obtained at admission which identified the later development of AKI during hospitalization with high sensitivity and specificity.
CAVEAT: Small single center study
Citations - To review the number of citations for this landmark paper, visit Google Scholar.