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Acute Mesenteric Ischemia


Preoperative risk factors for short-term postoperative mortality of acute mesenteric ischemia after laparotomy: A Systemic Review and Meta-Analysis.
Wu W, Liu J, Zhou Z.
Emerg Med Int. 2020 Oct 5;2020:1382475.

Rationale for inclusion:  Meta-analysis including 20 studies and 5011 patients that identifies preoperative risk factors associated with mortality following laparotomy for acute mesenteric ischemia. Understanding these risk factors may help improve perioperative decision making.

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Vasodilator therapy and mortality in nonocclusive mesenteric ischemia: A Nationwide Observational Study.
Takiguchi T, Nakajima M, Ohbe H, Sasabuchi Y, Matsui H, Fushimi K, Kim S, Yokota H, Yasunaga H.
Crit Care Med. 2020 May;48(5):e356-e361.

Rationale for inclusion: Large retrospective cohort study demonstrating vasodilatory therapy is associated with lower in-hospital mortality and prevalence of abdominal surgery in patients with nonocclusive mesenteric ischemia. 

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The role of endovascular therapy in acute mesenteric ischemia.
Ierardi AM, Tsetis D, Sbaraini S, Angileri SA, Galanakis N, Petrillo M, Patella F, Panella S, Balestra F, Lucchina N, Carrafiello G.
Ann Gastroenterol. 2017; 30(5): 526–533

Rationale for inclusion: This is an online review using PubMed that identified 18 articles from 2005 to 2016. Patients with arterial mesenteric ischemia treated with endovascular approach, the technical success rate was high (up to 100%). Technical success rate and clinical success of patients with acute venous mesenteric ischemia approached with endovascular treatment was 74-100% and 87.5-100%, respectively.

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Outcome of acute mesenteric ischemia in the intensive care unit: a retrospective, multicenter study of 780 cases.
Leone M, Bechis C, Baumstarck K, Ouattara A, Collange O, Augustin P, Annane D, Arbelot C, Asehnoune K, Baldési O, Bourcier S, Delapierre L, Demory D, Hengy B, Ichai C, Kipnis E, Brasdefer E, Lasocki S, Legrand M, Mimoz O, Rimmelé T, Aliane J, Bertrand PM, Bruder N, Klasen F, Friou E, Lévy B, Martinez O, Peytel E, Piton A, Richter E, Toufik K, Vogler MC, Wallet F, Boufi M, Allaouchiche B, Constantin JM, Martin C, Jaber S, Lefrant JY.
Intensive Care Med. 2015 Apr;41(4):667-76.

Rationale for inclusion: This study is a multi-center, retrospective study conducted in 43 French intensive care units, 38 of which were public hospitals. The authors identified 780 patients with acute mesenteric ischemia with 58% of those patients not surviving to ICU discharge. Multiple patient characteristics were more common in non-survivors (older age, presence of cancer, shock, and higher lactates; to name a few).

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Evaluation of acute mesenteric ischemia: accuracy of biphasic mesenteric multi-detector CT angiography.
Aschoff AJ, Stuber G, Becker BW, Hoffmann MH, Schmitz BL, Schelzig H, Jaeckle T.
Abdom Imaging. 2009 May-Jun;34(3):345-57.

Rationale for inclusion: This study examines 79 patients with acute mesenteric ischemia and essentially validates multi-detector row helical computed tomography as an accurate and rapid diagnostic tool.

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Identification of risk factors for perioperative mortality in acute mesenteric ischemia.
Acosta-Merida MA, Marchena-Gomez J, Hemmersbach-Miller M, Roque-Castellano C, Hernandez-Romero JM.
World J Surg. 2006 Aug;30(8):1579-85.

Rationale for inclusion: This is a retrospective study over a 10-year period that examines 132 patients undergoing operative therapy for acute mesenteric ischemia that identifies predictors of perioperative mortality.

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Bedside diagnostic minilaparoscopy in the intensive care patient.
Gagné DJ, Malay MB, Hogle NJ, Fowler DL.
Surgery. 2002 May;131(5):491-6.

Rationale for inclusion: This paper represents one of the initial descriptions of bedside laparoscopy in the intensive care unit for the identification of intestinal and intra-abdominal pathologies in the patient with acidosis, abdominal pain, and suspected mesenteric ischemia.

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Acute mesenteric ischemia caused by spontaneous isolated dissection of the superior mesenteric artery: treatment by percutaneous stent placement.
Leung DA, Schneider E, Kubik-Huch R, Marincek B, Pfammatter T.
Eur Radiol. 2000;10(12):1916-9.

Rationale for inclusion: This case report is likely the first published experience of completely percutaneous stenting of the superior mesenteric artery for a flow-limiting dissection.

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Long-term results after surgery for acute mesenteric ischemia.
Klempnauer J, Grothues F, Bektas H, Pichlmayr R.
Surgery. 1997 Mar;121(3):239-43.

Rationale for inclusion: This work is unique in its assessment of long-term outcomes after surgical intervention for acute mesenteric ischemia (AMI). Similar to other critical vascular pathologies involving tissue loss, the authors find the 5-year survival rate after surgical intervention for AMI is 50%.

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Acute mesenteric ischemia: improved results--a retrospective analysis of ninety-two patients.
Levy PJ, Krausz MM, Manny J.
Surgery. 1990 Apr;107(4):372-80.

Rationale for inclusion: The authors of this study compare a historic cohort of patients undergoing only bowel resection and anastomosis for acute mesenteric ischemia to a more modern cohort of patients that underwent bowel resection with varying patients receiving revascularization, second-look procedures, and delayed anastomosis creation with improved survival in the latter group. The authors also propose an algorithm for the management of patients with acute mesenteric ischemia.

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