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GI - Liver: Hepatorenal syndrome


Hepatorenal syndrome: Update on diagnosis and treatment.
Baraldi O, Valentini C, Donati G, Comai G, Cuna V, Capelli I, Angelini ML, Moretti MI, Angeletti A, Piscaglia F, La Manna G.
World J Nephrol. 2015 Nov 6;4(5):511-20.

Rationale for inclusion: Good summary of current treatment modalities (the usual standbys of terlipressin and albumin).

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Transplantation of cadaveric kidneys from patients with hepatorenal syndrome. Evidence for the functionalnature of renal failure in advanced liver disease.
Koppel MH, Coburn JW, Mims MM, Goldstein H, Boyle JD, Rubini ME.
N Engl J Med. 1969 Jun 19;280(25):1367-71.

Rationale for inclusion: Landmark surgical proof of concept that the kidneys are not the culprit in hepatorenal syndrome.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

Liver trauma and the hepatorenal syndrome. 
Orr TG, Helwig FC.
Ann Surg. 1939 Oct;110(4):682-92.

Rationale for inclusion: This is a review of five cases of liver trauma complicated by renal failure.  Interesting also as a window into the studies and imaging available at the time.

Citations  - To review the number of citations for this landmark paper, visit Google Scholar.

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