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- Western Trauma Association Critical Decisions in Trauma: Nonoperative Management of Adult Blunt Hepatic Trauma
- Published on Dec 1, 2009 from J Trauma
- No abstract available
- Toll-Like Receptors in Ischemia-Reperfusion Injury
- Published on Jul 1, 2009 from Shock
- Ischemia-reperfusion (I/R) injuries are implicated in a large array of pathological conditions such as myocardial infarction, cerebral stroke, and hepatic, renal, and intestinal ischemia, as well as following cardiovascular and transplant surgeries. …
- Multicenter Study of Early Lactate Clearance As A Determinant of Survival in Patients With Presumed Sepsis
- Published on Jul 1, 2009 from Shock
- We sought to determine (a) if early lactate clearance is associated with improved survival in emergency department patients with severe sepsis and (b) the concordance between central venous oxygen saturation (ScvO2) optimization and lactate clearance…
- Improvements in Early Mortality and Coagulopathy are Sustained Better in Patients With Blunt Trauma After Institution of a Massive Transfusion Protocol in a Civilian Level I Trauma Center
- Published on Jun 1, 2009 from J Trauma
- Introduction: Transfusion practices across the country are changing with aggressive use of plasma (fresh-frozen plasma [FFP]) and platelets during massive transfusion with current military recommendations to use component therapy at a 1:1:1 ratio of …
- Staff Commitment to Trauma Care Improves Mortality and Length of Stay at a Level I Trauma Center
- Published on May 1, 2009 from J Trauma
- Background: Optimizing human resources at trauma facilities may increase quality of care. The purpose of this study was to assess whether staffing changes within a Level I trauma center improved mortality and shortened length of stay (LOS) for trauma…
- Retraction
- Published on May 1, 2009 from Shock
- No abstract available
- Validation of Postinjury Multiple Organ Failure Scores
- Published on May 1, 2009 from Shock
- Most multiple organ failure (MOF) scores were developed over a decade ago, but little has been done in terms of validation and to understand the differences between populations identified by each of them. Given the lack of a gold standard, validation…
- [beta]-BLOCKERS IN SEPSIS: REEXAMINING THE EVIDENCE
- Published on Feb 1, 2009 from Shock
- Sepsis remains the leading cause for noncardiac intensive care unit deaths in the United States. Despite recent advances in the treatment of this devastating condition, mortality and morbidity remain unacceptably high. Sepsis is characterized by a mu…
- Rifle Classification for Predicting in-Hospital Mortality in Critically Ill Sepsis Patients
- Published on Feb 1, 2009 from Shock
- Severe sepsis and septic shock, often complicated by acute kidney injury (AKI), are the most common causes of mortality in noncoronary intensive care units (ICUs). This study investigates the outcomes of critically ill patients with sepsis and elucid…
- Cardioprotection By Hydrogen Sulfide: Suspended Animation, Inflammation, and Apoptosis
- Published on Feb 1, 2009 from Shock
- No abstract available
- Histological and Histochemical Methods: Theory and Practice, 4Th Edition
- Published on Oct 1, 2008 from Shock
- No abstract available
- Janeway's Immunobiology, 7Th Edition
- Published on Jun 1, 2008 from Shock
- No abstract available
- BERBERINE INHIBITS CYTOSOLIC PHOSPHOLIPASE A2 AND PROTECTS AGAINST LPS-INDUCED LUNG INJURY AND LETHALITY INDEPENDENT OF THE [alpha]2-ADRENERGIC RECEPTOR IN MICE
- Published on May 1, 2008 from Shock
- Acute lung injury is still a significant clinical problem having a high mortality rate despite significant advances in antimicrobial therapy and supportive care made in the past few years. Our previous study demonstrated that berberine (Ber) remarkab…
- Hexosamine Biosynthesis and Protein O-Glycosylation: the First Line of Defense Against Stress, Ischemia, and Trauma
- Published on Apr 1, 2008 from Shock
- An early and rapid response to severe injury or trauma is the development of hyperglycemia, which has long been thought to be an essential survival response by providing fuel for vital organ systems and facilitating mobilization of interstitial fluid…
- CYTOKINE-INDUCED EPITHELIAL PERMEABILITY CHANGES ARE REGULATED BY THE ACTIVATION OF THE p38 MITOGEN-ACTIVATED PROTEIN KINASE PATHWAY IN CULTURED CACO-2 CELLS
- Published on Apr 1, 2008 from Shock
- Increased intestinal/epithelial permeability in sepsis and endotoxemia has been noted to be induced by proinflammatory cytokines such as interferon-[gamma], TNF-[alpha], and IL-1[beta]. The p38 mitogen-activated protein kinase (MAPK) signaling pathwa…
- Air Medical Response to Traumatic Brain Injury: A Computer Learning Algorithm Analysis
- Published on Apr 1, 2008 from J Trauma
- Background: The role of air medicine in traumatic brain injury (TBI) has been studied extensively using trauma registries but remains unclear. Learning algorithms, such as artificial neural networks (ANN), support vector machines (SVM), and decision …
- Role of Toll-Like Receptors in the Development of Sepsis
- Published on Mar 1, 2008 from Shock
- The outcome of sepsis and septic shock has not significantly improved in recent decades despite the development of numerous drugs and supportive care therapies. To reduce sepsis-related mortality, a better understanding of molecular mechanism(s) asso…
- Prognostic Value of Mortality in Emergency Department Sepsis Score, Procalcitonin, and C-Reactive Protein in Patients With Sepsis At the Emergency Department
- Published on Mar 1, 2008 from Shock
- The prognostic value of procalcitonin (PCT) in patients with sepsis at the emergency department (ED) has not been evaluated. We conducted a prospective observational study to compare the prognostic value of PCT on sepsis and compared with a validated…
- Outcomes for Trauma: Is There an End (Result) in Sight?
- Published on Jan 1, 2008 from J Trauma
- No abstract available
- Thermal Injury Elevates the Inflammatory Monocyte Subpopulation in Multiple Compartments
- Published on Dec 1, 2007 from Shock
- Recent publications have demonstrated that human resident and inflammatory monocyte (IM) subpopulations have equivalents in rodents. The effect of thermal injury upon these subpopulations has not been studied. Mice were given a scald burn and killed …